https://https://au.trip.com/toplist/tripbest/recommend/key-west/best-upscale-hotels/100200177690
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4-Star Select Hotels
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Top 10 4-Star Select Hotels in Key West [2025]

Southernmost Beach Resort
Southernmost Beach Resort
Southernmost Beach Resort
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Southernmost Beach Resort

Southernmost Beach Resort

8.2
/5
108 reviews
Duval | 1.9 km from downtown
Address: 1319 Duval St
Highlights:
󰋙Recently renovated sea view rooms with Atlantic Ocean views
󰋙Modern comfort with stunning Atlantic Ocean views
H2O Suites- Adults Only
H2O Suites- Adults Only
H2O Suites- Adults Only
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H2O Suites- Adults Only

H2O Suites- Adults Only

9.6
/5
99 reviews
Duval | 1.8 km from downtown
Address: 1212 Simonton St
Highlights:
󰋙Year - round rooftop pool for relaxation
󰋙Year-round rooftop pool with amazing vibes
Opal Key Resort & Marina
Opal Key Resort & Marina
Opal Key Resort & Marina
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Opal Key Resort & Marina

Opal Key Resort & Marina

8.7
/5
101 reviews
Downtown Key West | 2.7 km from downtown
Address: 245 Front St
Highlights:
󰋄Breathtaking sunset views at Sunset Deck
󰋙Serene ocean views with modern accommodations

No.

4

Ocean Key Resort & Spa, a Noble House Resort
Ocean Key Resort & Spa, a Noble House Resort
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Ocean Key Resort & Spa, a Noble House Resort

Ocean Key Resort & Spa, a Noble House Resort

9.0
/5
98 reviews
Duval | 2.8 km from downtown
Address: 0 Duval St
Highlights:
󰋄Beautiful sunsets from ocean-facing balconies
󰋙Balcony rooms overlooking Gulf or Duval

No.

5

The Pier House Resort
The Pier House Resort
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The Pier House Resort

The Pier House Resort

8.6
/5
102 reviews
Duval | 2.7 km from downtown
Address: One Duval Street
Highlights:
󰋄Perfect key west sunset views by waterfront
󱒾Enjoy private white sands in lush tropical gardens

No.

6

Santa Maria Suites Resort
Santa Maria Suites Resort
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Santa Maria Suites Resort

Santa Maria Suites Resort

9.4
/5
102 reviews
Duval | 1.7 km from downtown
Address: 1401 Simonton St
Highlights:
󰋄Tranquil retreat surrounded by garden views
󰋙Relax at pool bar with fresh juices

No.

7

Hyatt Centric Key West Resort and Spa
Hyatt Centric Key West Resort and Spa
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Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

8.6
/5
108 reviews
Downtown Key West | 2.5 km from downtown
Address: 601 Front St
Highlights:
󰋄Magical sunset views from waterfront location
󰋙Private balcony rooms with stunning ocean views

No.

8

The Marker Waterfront Resort Key West
The Marker Waterfront Resort Key West
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The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

8.8
/5
100 reviews
Downtown Key West | 2.3 km from downtown
Address: 200 William St
Highlights:
󰋄Beautiful harbor view in historic Key West
󰋄Tropical and serene courtyard garden views

No.

9

The Saint Hotel Key West, Autograph Collection
The Saint Hotel Key West, Autograph Collection
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The Saint Hotel Key West, Autograph Collection

The Saint Hotel Key West, Autograph Collection

8.7
/5
67 reviews
Duval | 2.5 km from downtown
Address: 417 Eaton St
Highlights:
󰋙Rooftop bar with Key West sunsets
󰋙Rooftop outdoor pool with stunning views
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