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Flights from Chicago to Santiago Starting at CNY 453

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Return

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Chicago to Santiago

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Airlines Flying from Chicago to Santiago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From AU$ 358
Spirit Airlines
From AU$ 388
United Airlines
From AU$ 515
Copa Airlines
From AU$ 518
American Airlines
From AU$ 518
Jetblue Airways
From AU$ 536
LATAM Airlines
From AU$ 536
Delta Air Lines
From AU$ 561
Avianca
From AU$ 587
Southwest Airlines
From AU$ 592
ANA airlines

Find more flights and airlines

Alternative Routes from Chicago to Santiago

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Chicago to Santiago.

  • Cheapest
    Frontier Airlines
    MDW
    19:17
    26h 23m
    2 transfer
    SCL
    22:40
    Midway International Airport - Arturo Merino Benitez Airport
    Mon, May 6Frontier Airlines
    AU$ 358
  • Spirit Airlines
    ORD
    20:59
    22h 56m
    2 transfer
    SCL
    20:55
    O'Hare International Airport - Arturo Merino Benitez Airport
    Wed, Apr 24Spirit Airlines
    AU$ 388
  • Spirit Airlines
    ORD
    20:59
    22h 56m
    2 transfer
    SCL
    20:55
    O'Hare International Airport - Arturo Merino Benitez Airport
    Wed, Apr 24Spirit Airlines
    AU$ 388
    Find More Flights

How do I find the cheapest flights?

  • When are flight from Chicago (CHI) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Chicago to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much are flights from Chicago (CHI) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around AU$ 1,487.
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12km, by taxi about 30 minutes.
  • How many airports in Santiago (SCL)?

    There are 1 airport(s) in Santiago (SCL): Arturo Merino Benitez Airport.

How to find a cheap flight from Chicago to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Chicago to Santiago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Chicago to Santiago

Cheapest direct flight price

AU$ 453

Off-season for travel

December

Peak season for travel

October

Flight distance

8,544.66km

Popular airline

American Airlines