Find Cheapest Airlines Flying from Mendoza to Santiago

Choose from 3 carriers that fly from Mendoza to Santiago, including Sky Airline, JetSMART Airlines, and LATAM Airlines. Enjoy the cheapest tickets on this route with Sky Airline.
Sky Airline logo Sky Airline
JetSMART Airlines logo JetSMART Airlines
LATAM Airlines logo LATAM Airlines
Airlines are determined based on actual purchased flight tickets from Mendoza to Santiago according to previous 12 months data from Trip.com.

Explore the cheapest flights from Mendoza to Santiago in the next three months. Based on Trip.com's data from the latest 7 days, one-way direct flights start at AU$ 75, and round-trip direct tickets start at AU$ 101.

Displayed flight fares from Mendoza to Santiago are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Mendoza to Santiago Flight Details

The distance between Mendoza and Santiago is approximately 195.84km. It takes around 6 hours 6 minutes on average to fly from Mendoza to Santiago. Based on Trip.com's data travel demand peaks in July. The off-season for travel is October.

Cheapest one-way flight priceAU$ 75
Cheapest return ticket priceAU$ 101
Off-season for travelOctober
Peak season for travelJuly
Flight distance195.84km
Average flight time6 hours 6 minutes
Popular airlineSky Airline
Flight statistics for the Mendoza–Santiago route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Mendoza to Santiago

What is the cheapest month for one-way flights from Mendoza to Santiago?

Average price of one-way flights from Mendoza to Santiago purchased by Trip.com users by month over the past 12 months.

According to Trip.com's data, the cheapest month for flights from Mendoza to Santiago is February, with an average price of AU$ 136. Conversely, the most expensive month is typically July, with an average price of up to AU$ 172.

AU$ 172
AU$ 154
AU$ 136
AU$ 118
    Cheapest
  • AU$ 146
    Mar
  • AU$ 142
    Apr
  • AU$ 156
    May
  • AU$ 167
    Jun
  • AU$ 172
    Jul
  • AU$ 148
    Aug
  • AU$ 167
    Sep
  • AU$ 141
    Oct
  • AU$ 154
    Nov
  • AU$ 171
    Dec
  • AU$ 157
    Jan
  • AU$ 136
    Feb

What's the cheapest day to fly from Mendoza to Santiago?

Data is based on the average flight price for each day of the week from Mendoza to Santiago on Trip.com over the past 12 months.

Based on Trip.com data from the past 12 months, the cheapest day to fly from Mendoza to Santiago is Wednesday, with average prices lower than on other days. Avoid Sunday, as prices are usually highest then.

AU$ 183
AU$ 159
AU$ 135
AU$ 111
    Cheapest
  • AU$ 164
    Mon
  • AU$ 156
    Tue
  • AU$ 135
    Wed
  • AU$ 151
    Thu
  • AU$ 144
    Fri
  • AU$ 150
    Sat
  • AU$ 183
    Sun

When is the cheapest day to fly from Mendoza to Santiago during Good Friday?

Data is based on the lowest one-way fares from Mendoza to Santiago during Good Friday, sourced from the Trip.com database over the last 3 days.

During Good Friday, the cheapest flights from Mendoza to Santiago are on Mar 31, with the lowest fare of AU$ 77.

AU$ 251
AU$ 164
AU$ 77
0
  • AU$ 77
    Mar 31
  • AU$ 208
    Apr 1
  • AU$ 91
    Apr 2
  • AU$ 80
    Apr 3
  • AU$ 80
    Apr 4
  • AU$ 251
    Apr 5

Flight FAQs

  • Which airlines offer the cheapest flights from Mendoza (MDZ) to Santiago (SCL)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as AU$ 75 on Cheapest nonstop routes (e.g. MDZ to SCL on Thu, Mar 19), while Sky Airline offers Cheapest nonstop round-trips from AU$ 101 departing on Fri, Mar 20 and returning on Mon, Mar 23.
  • At the moment, you can catch a direct flight from Mendoza to Santiago with the following airlines, including: Sky Airline LATAM Airlines JetSMART Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 6 hours 6 minutes to fly from Mendoza (MDZ) to Santiago (SCL).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Mendoza to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 24 flight per week flying from Mendoza to Santiago. You can check the weekly schedule for popular airlines on this route below: Sky Airline: S/M/T/W/T/F/- -- H2528 (20:58) LATAM Airlines: S/M/T/W/-/F/S -- LA435 (11:58)
  • To find best deals on flights from Mendoza to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Mar 19, with one-way flights priced at just AU$ 75.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Sky Airline.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Mendoza to Santiago is October, when demand for travel is lower.
  • After crunching the numbers on our March flight calendar, it's currently cheapest to fly from Mendoza to Santiago on March 31, 2026 with Sky Airline, with prices starting at AU$ 65.
  • You can land at any one of the following hubs in Santiago, with El Plumerillo International Airport to Arturo Merino Benitez International Airport (MDZ-SCL) is by far the most common option on this route: Arturo Merino Benitez International Airport (SCL).
  • The time difference between Santiago and Mendoza is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Mendoza toSantiago

Which airlines offer the cheapest nonstop flights from Mendoza to Santiago?

Data is based on the average price of all nonstop flights from Mendoza to Santiago on Trip.com in the past 12 months.

Based on Trip.com data from the past 12 months, Sky Airline offers the cheapest nonstop flights from Mendoza to Santiago, with an average price of AU$ 148.

AU$ 125
AU$ 148
AU$ 172
AU$ 195
AU$ 218
Sky Airline
AU$ 148
Sky Airline
JetSMART Airlines
AU$ 153
JetSMART Airlines
Aerolineas Argentinas
AU$ 162
Aerolineas Argentinas
LATAM Airlines
AU$ 218
LATAM Airlines

Which airlines operate the most flights from Mendoza to Santiago?

Data is based on the number of flights from Mendoza to Santiago operated by each airline on Trip.com in the past month.

Based on Trip.com data from the past month, LATAM Airlines operates the most flights from Mendoza to Santiago, with 15 flight per week.

0
3
9
15
LATAM Airlines
15
LATAM Airlines
Sky Airline
14
Sky Airline
Delta Air Lines
8
Delta Air Lines
Iberia
7
Iberia
American Airlines
3
American Airlines
JetSMART Airlines
3
JetSMART Airlines

How many flights are there each day from Mendoza to Santiago?

The data is based on the flight numbers for each day of the week from Mendoza to Santiago within the Trip.com database over the past month.

Based on Trip.com data from the past month, the most flights from Mendoza to Santiago depart on Friday, and the fewest flights depart on Thursday.

40
29
17
6
Highest
32
Mon
24
Tue
24
Wed
17
Thu
40
Fri
25
Sat
36
Sun