Hotels near Museum of Life and Science

Hotels Near Museum of Life and Science in Durham

Enter your dates for the latest hotel rates and availability.

Swipe up to view more
Filter by:
Hotel Star Rating
≤2345
Guest Rating
Amazing 9+Great 8+Good 7+Pleasant 6+

Best Hotels near Museum of Life and Science

Choose your travel dates to see the latest prices and deals.
Most Booked
Lowest Price
Closest to Downtown
Highest Rated
Residence Inn Durham McPherson/Duke University Medical Center Area Hotels near Museum of Life and Science
Residence Inn Durham McPherson/Duke University Medical Center Area Hotels near Museum of Life and ScienceResidence Inn Durham McPherson/Duke University Medical Center Area Hotels near Museum of Life and Science
3.25km from Museum of Life and Science
Eat, sleep, and relax at the fully renovated all-suite Residence Inn Durham McPherson/Duke University Medical Center Area. Boasting a prime location near Duke University, North Carolina Central University and Durham Performing Arts Center, our hotel makes it easy to discover some of the area's top attractions. Enjoy spacious suites featuring separate areas for living, cooking and sleeping; and then take in a game at the nearby Durham Bulls Athletic Park or a Broadway production at DPAC. Finish any work tasks you may have using our free Wi-Fi and ergonomic workstation, then prepare yourself a delicious meal with the help of your room's full kitchen. Start your day at our complimentary breakfast buffet. After fueling up, work up a sweat at our fitness center using our cardio equipment and free weights. The hotel offers complimentary transportation services, which must be reserved a minimum 24 hours in advance. Wheelchair accessible transportation is also available.
Great
81 reviews
9.0/10
Price from
AU$ 239
per night
Check Availability
Hilton Garden Inn Durham-University Medical Center Hotels near Museum of Life and Science
Hilton Garden Inn Durham-University Medical Center Hotels near Museum of Life and ScienceHilton Garden Inn Durham-University Medical Center Hotels near Museum of Life and Science
3.33km from Museum of Life and Science
Uniquely situated at Main Street near the corner of the 9th Street district, between Duke University's East and West Campus, the hotel is ideally placed to serve Duke University and the Duke Medical Center. Guests of the hotel will have easy access to the Duke campus or explore downtown Durham hot spots such as Brightleaf Square and The American Tobacco Historic District. Walk down to 9th Street, Duke's favorite spot for shopping, restaurants and student life. Enjoy complimentary hotel shuttle service within a 5-mile radius. The hotel offers the freshest approach to architecture and interior design in Durham, with a full array of services including WiFi access, HDTV, stylish beverage services, and a restaurant. Hotel features: 128 state-of-the-art overnight rooms Restaurant serving breakfast and dinner daily Lounge featuring signature drinks Complimentary fitness center featuring Precor cardio and weight training equipment Complimentary wireless internet throughout the hotel Indoor pool Outdoor patio with fire pit and luxury lounge furniture Meeting room features: 1,456 sq. ft. meeting room (56 feet x 26 feet x 11 feet) Dinner events up to 88 Classroom seating up to 72 Theater seating up to 150 Divisible into 2 rooms Additional boardroom seats 12 comfortably
Amazing
125 reviews
9.4/10
Price from
AU$ 260
per night
Check Availability
21C Museum Hotel Durham Hotels near Museum of Life and Science
21C Museum Hotel Durham Hotels near Museum of Life and Science21C Museum Hotel Durham Hotels near Museum of Life and Science
3.71km from Museum of Life and Science
Art Museum Meets Boutique Hotel in downtown Durham, North Carolina. Standing tall and proud in the center of downtown Durham, 21c Museum Hotel Durham is a full-service boutique hotel located within a contemporary art museum offering more than 10,500 square feet of art filled exhibition and event space. The 21c Museum Hotel Durham offers 125 luxurious guest rooms and suites, and The Counting House restaurant featuring Chef Melanie Wilkerson's seasonal North Carolina menus.
Very Good
100 reviews
8.2/10
Price from
AU$ 249
per night
Check Availability
Durham
You Might Like
Durham Hotels Including BreakfastDurham Hotels With Twin RoomDurham Hotels With 1 Double BedDurham Hotels With Swimming PoolDurham Hotels With Free Cancellation
The Lodge at Duke Medical Center Hotels near Museum of Life and Science
The Lodge at Duke Medical Center Hotels near Museum of Life and ScienceThe Lodge at Duke Medical Center Hotels near Museum of Life and Science
4.01km from Museum of Life and Science
With a stay at The Lodge at Duke Medical Center in Durham, you'll be in the business district, a 3-minute walk from Duke University Hospital and a 4-minute drive from Duke University. This hotel is 8.4 mi (13.5 km) from Research Triangle Park and 10.1 mi (16.2 km) from University of North Carolina. Make use of convenient amenities such as complimentary wireless internet access, a fireplace in the lobby, and a banquet hall. Grab a bite from the snack bar/deli serving guests of The Lodge at Duke Medical Center. Featured amenities include dry cleaning/laundry services, a 24-hour front desk, and luggage storage. Free self parking is available onsite. Make yourself at home in one of the 146 air-conditioned rooms featuring refrigerators and LED televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with showers feature complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Very Good
101 reviews
8.3/10
Price from
AU$ 171
per night
Check Availability
Aloft Durham Downtown Hotels near Museum of Life and Science
Aloft Durham Downtown Hotels near Museum of Life and ScienceAloft Durham Downtown Hotels near Museum of Life and Science
4.03km from Museum of Life and Science
Immerse yourself in the excitement of Bull City when you stay at Aloft Durham Downtown. Settled in the heart of American Tobacco, Durham's thriving entertainment district, our hotel in downtown Durham, NC, is within walking distance to an array of charming boutiques, local restaurants, Durham Bulls Athletic Park and Durham Performing Arts Center, lovingly known as DPAC. Check-in to our tech-forward hotel and grab a crafted cocktail at our swanky lobby bar. Our loft-inspired rooms offer a unique space to unplug and recharge. Plunge into our plush platform beds topped with plump pillows and prepare to press the snooze button a few times in the morning. Seamlessly transition between work and play during your business trip to our downtown Durham, NC, hotel with modern amenities such as flat-panel TVs, ample workstations and free high-speed Wi-Fi. With stunning city views, an outdoor pool and an unrivaled location, Aloft Durham Downtown offers the ideal getaway for savvy travelers and jet set go-getters alike.
Great
85 reviews
9.0/10
Price from
AU$ 308
per night
Check Availability
SpringHill Suites Durham City View Hotels near Museum of Life and Science
SpringHill Suites Durham City View Hotels near Museum of Life and ScienceSpringHill Suites Durham City View Hotels near Museum of Life and Science
4.55km from Museum of Life and Science
Travel in style at new SpringHill Suites by Marriott®, the all-suite, Durham, NC hotel just one block from downtown that seamlessly blends design and functionality offering the modern amenities you need to stay refreshed and focused - all at an affordable price. Spacious suites, a vibrant lobby and over 3,000 sq. ft. of meeting space offer flexible options perfect for working, gathering or relaxing. Take the stress out of travel with our free Wi-Fi and on-site fitness center. Our Market is open 24/7 for snacks and necessities. Enjoy our complimentary breakfast with fresh choices for a customized start to your day. Spend your stay exploring all that our city has to offer, including the adjacent downtown area where the Durham Bulls play and where you’ll find DPAC and the American Tobacco Campus. Duke University, North Carolina Central University (NCCU) and the Research Triangle Park (RTP) are also close by. Quite simply, from business trips to leisurely journeys, SpringHill Suites is a breath of fresh air.
Great
107 reviews
9.0/10
Price from
AU$ 207
per night
Check Availability
Home2 Suites by Hilton Durham University Medical Center Hotels near Museum of Life and Science
Home2 Suites by Hilton Durham University Medical Center Hotels near Museum of Life and ScienceHome2 Suites by Hilton Durham University Medical Center Hotels near Museum of Life and Science
4.78km from Museum of Life and Science
Our pet-friendly hotel is ideally located at the intersection of Highway I-85 & Cole Mill Rd. We’re just two miles from Duke University and Duke Medical Center, and six miles from North Carolina Central University. Downtown Durham attractions such as Durham Performing Arts Center (DPAC), Durham Bulls Athletic Park, restaurants, and bars are a short five-minute drive away. Enjoy free breakfast, WiFi, and a five-mile radius shuttle during your stay, as well as access to our fitness center, laundry facilities and indoor heated pool.
Amazing
83 reviews
9.4/10
Price from
AU$ 211
per night
Check Availability
AC Hotel Durham Hotels near Museum of Life and Science
AC Hotel Durham Hotels near Museum of Life and ScienceAC Hotel Durham Hotels near Museum of Life and Science
4.9km from Museum of Life and Science
Experience a unique combination of timeless European design, comfort and authentic southern hospitality when staying at the AC Hotel Durham. Located adjacent to Duke University, just four miles from the eclectic Downtown Durham, you’ll enjoy the city’s celebrated food scene and award-winning restaurants. Start your day with the European-inspired breakfast at our hotel restaurant, AC Kitchen. Then join us in the evening at the AC Lounge for tapas, Spanish wines, handcrafted cocktails and craft brews, all of which have been carefully curated to encourage a perfectly precise experience. Our 24-hour fitness center helps you stay active with a Peloton bike, an assortment of free weights, cardio machines and yoga mats. Our thoughtfully designed guest rooms feature plush bedding, free Wi-Fi and luxurious bath amenities. Our hotel near downtown Durham, NC, provides all the things you want and nothing that you don't while encouraging the ability to connect to the city of Raleigh-Durham in a stylish way.
Very Good
115 reviews
8.9/10
Price from
AU$ 209
per night
Check Availability
Millennium Durham Hotels near Museum of Life and Science
Millennium Durham Hotels near Museum of Life and ScienceMillennium Durham Hotels near Museum of Life and Science
5.25km from Museum of Life and Science
You’ll find Millennium Durham Hotel minutes away from Duke University Hospital and Duke University – and an easy drive to charming downtown Durham, where you'll also discover gems such as Durham Bulls Stadium, Bennett Place, Carolina Theater and Durham Performing Arts Center. In addition to 316 suites and rooms, including many double queen rooms perfect for teams, this luxury hotel in Durham is sure to providing you with a relaxing stay.
Good
125 reviews
7.6/10
Price from
AU$ 130
per night
Check Availability
DoubleTree Suites by Hilton Raleigh - Durham Hotels near Museum of Life and Science
DoubleTree Suites by Hilton Raleigh - Durham Hotels near Museum of Life and ScienceDoubleTree Suites by Hilton Raleigh - Durham Hotels near Museum of Life and Science
13.3km from Museum of Life and Science
Welcome to DoubleTree Guest Suites Raleigh/Durham hotel, an all-suite, full-service hotel that offers value and comfort in a great location. Situated lakeside by the famed Research Triangle Park (RTP), our hotel is only ten minutes from Raleigh-Durham International Airport (RDU). With a mini-resort atmosphere, DoubleTree provides accommodations for both the leisure and corporate traveler with an array of services and amenities. Features Include: Business center with complimentary services, exercise room, flexible meeting space for two to 130 attendees, scenic lakeview terrace for wedding ceremonies and receptions, team building exercises, company picnics and themed banquets, complimentary transportation to the airport, businesses, restaurants and shopping, Extensive recreational facilities include indoor/outdoor swimming pools, a lake with paddleboats, sand volleyball, basketball, fitness center, walking trails, and bicycle paths.
Very Good
105 reviews
8.9/10
Price from
AU$ 182
per night
Check Availability
See all Hotels near Museum of Life and Science

Top Pick Hotels near Museum of Life and Science

See all
Check out our most booked hotels near Museum of Life and Science from the past 30 days!
No.1
Hampton Inn & Suites Durham/North I-85 Hotels near Museum of Life and Science
8.8/10
103 review

Hampton Inn & Suites Durham/North I-85

Durham | 1.36KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.2
Red Roof Inn Durham - Duke University Medical Center Hotels near Museum of Life and Science
6.7/10
96 review

Red Roof Inn Durham - Duke University Medical Center

Durham | 2.17KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.3
Comfort Inn & Suites Durham Near Duke University Hotels near Museum of Life and Science
8.5/10
102 review

Comfort Inn & Suites Durham Near Duke University

Durham | 3.24KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.4
Unscripted Durham - JDV by Hyatt Hotels near Museum of Life and Science
8.2/10
97 review

Unscripted Durham - JDV by Hyatt

Durham | 3.65KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.5
Courtyard Durham Near Duke University/Downtown Hotels near Museum of Life and Science
8.1/10
100 review

Courtyard Durham Near Duke University/Downtown

Durham | 3.41KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.6
University Inn Duke Hotels near Museum of Life and Science
9.5/10
136 review

University Inn Duke

Durham | 3.97KM from Museum of Life and Science
"Clean and tidy""Great rooms"
Select dates to view prices
No.7
The Durham Hotel Hotels near Museum of Life and Science
8.8/10
97 review

The Durham Hotel

Durham | 3.6KM from Museum of Life and Science
"Good Location"
Select dates to view prices
No.8
Cozy  Ranch New Build 3 bed 2 bath Hotels near Museum of Life and Science
/10
0 review

Cozy Ranch New Build 3 bed 2 bath

Durham | 2.91KM from Museum of Life and Science
"Good Location"
Select dates to view prices

Frequently asked questions

How much is a hotel near Museum of Life and Science per night?

According to Trip.com, the average price for a one-night stay at a hotel near Museum of Life and Science in Durham is AU$ 158. Prices can change frequently, so this rate is just an estimate.

What’s the average price of hotels near Museum of Life and Science this weekend?

According to Trip.com, the average price for a one-night weekend stay at a hotel near Museum of Life and Science in Durham is around AU$ 244. Keep in mind that prices can vary frequently, so this rate is just an estimate.

What are the best hotels to stay near Museum of Life and Science?

If you're having trouble deciding on a hotel, consider Hampton Inn & Suites Durham/North I-85 (from AU$ 209),Red Roof Inn Durham - Duke University Medical Center (from AU$ 97) and Hilton Garden Inn Durham-University Medical Center (from AU$ 234) . These hotels are highly rated, so it's a good idea to book in advance.

What are the best hotels near Museum of Life and Science with pools?

When summer arrives, there’s nothing like a family trip to Museum of Life and Science in Durham to make the most of sunny days. Hilton Garden Inn Durham-University Medical Center (from AU$ 234),Hampton Inn & Suites Durham/North I-85 (from AU$ 209) and Comfort Inn & Suites Durham Near Duke University (from AU$ 164) are popular hotels with pools where you can relax and enjoy the summer vibe.

Which hotels near Museum of Life and Science offer gyms?

What hotels near Museum of Life and Science have parking?

If you're planning a road trip to Durham Museum of Life and Science, you might want to stay at Hilton Garden Inn Durham-University Medical Center (from AU$ 234),Hampton Inn & Suites Durham/North I-85 (from AU$ 209) and Red Roof Inn Durham - Duke University Medical Center (from AU$ 97) , these hotels all have parking available.

What hotels near Museum of Life and Science have the best breakfast?

A great breakfast is the perfect way to brace yourself for the day ahead. If you're looking to stay at a hotel in Durham near Museum of Life and Science that serves up a top-notch breakfast, consider 21C Museum Hotel Durham (from AU$ 249),Hampton Inn & Suites Durham/North I-85 (from AU$ 209) and Unscripted Durham - JDV by Hyatt (from AU$ 203) . These hotels are really popular, so make sure you book in advance.

What are hotels near Museum of Life and Science with free Wi-Fi?

For anyone who needs to stay connected during travel, free Wi-Fi is a must. Hampton Inn & Suites Durham/North I-85 (from AU$ 209),Hilton Garden Inn Durham-University Medical Center (from AU$ 234) and Holiday Inn Express Durham (from AU$ 187) are popular hotels with free Wi-Fi.

Durham weather

Today
2 Aug, 2025
18
°
Showers
Showers 18 - 26℃
2 Aug, 2025
ShowersShowers
18 - 26℃
3 Aug, 2025
Intermittent cloudsIntermittent clouds
16 - 27℃
4 Aug, 2025
Intermittent cloudsIntermittent clouds
19 - 29℃
5 Aug, 2025
Mostly cloudyMostly cloudy
20 - 26℃
6 Aug, 2025
ThunderstormsThunderstorms
21 - 28℃
7 Aug, 2025
ThunderstormsThunderstorms
20 - 24℃
8 Aug, 2025
ThunderstormsThunderstorms
19 - 26℃

Hotels Near Museum of Life and Science in Durham – Best Accommodation Options

Highest PriceAU$ 1,580
Lowest PriceAU$ 101
Number of Reviews2,649
Total Properties120
Average Price (Weekdays)AU$ 364
Average Price (Weekends)AU$ 402