San Telmo is a must on Sunday for its famous street fair. Go around noon and plan to spend the day. Bus #29 which you pick up on Corrientes in front of the Carrefour supermarket takes you there. It's also a 30 minute walk. I would get off at Plaza de Mayo and walk along Defensa street to get a full view of the fair. Favorite restaurants: Desnivel for budget and the quirky aand La Brigada for less concern for budget and a more traditional atmosphere. I also do Desnivel!
Our home is located in San Telmo, so you can simply walk out the door and start experiencing some of San Telmo. Pop-up art galleries, late-night bars and street murals lend old San Telmo a bohemian vibe. Lined with antiques dealers and raucous steakhouses, Defensa street (which begins 3 blocks from our home) cuts through Plaza Dorrego, where a flea market and street performers attract tourists every Sunday. In Parque Lezama, paths wind around tall jacaranda trees and the Italianate Museo Histórico Nacional. Upscale tango dinner-show venues dot the neighborhood.
A fashion and very popular place to be, lots of antiques and flee markets , safe and lot of bars
They have a fun antique fair during weekends, It is also one of the oldest neighbourhoods of the city with lots of history.
This is a cultural gem. Sundays they host a street fair that goes on for blocks...and blocks.