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Low Price Flights from Santiago to Cusco

Find Cheapest Airlines Flying from Santiago to Cusco

Choose from 1 carriers that fly from Santiago to Cusco, including LATAM Airlines, Enjoy the cheapest tickets on this route with LATAM Airlines.
LATAM Airlines logo LATAM Airlines
Airlines are determined based on actual purchased flight tickets from Santiago to Cusco according to previous 12 months data from Trip.com.

Explore the cheapest flights from Santiago to Cusco in the next three months. Based on Trip.com's data from the latest 7 days, one-way direct flights start at AU$ 162, and round-trip direct tickets start at AU$ 365.

      • Cheapest nonstop
        SCL 14:40
        3h 30m
        Direct
        CUZ 17:10
        Santiago - Cusco | Tue, Jun 2 | LATAM Airlines
        CUZ 09:30
        3h 20m
        Direct
        SCL 13:50
        Cusco - Santiago | Sat, Jun 6 | LATAM Airlines
        AU$ 365 AU$ 413
        12% off
        12% off
        AU$ 413 AU$ 365
      • SCL 19:45
        3h 30m
        Direct
        CUZ 22:15
        Santiago - Cusco | Thu, Apr 23 | LATAM Airlines
        CUZ 09:30
        3h 20m
        Direct
        SCL 13:50
        Cusco - Santiago | Tue, Apr 28 | LATAM Airlines
        AU$ 375 AU$ 413
        9% off
        9% off
        AU$ 413 AU$ 375
      • SCL 20:20
        10h 50m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Fri, Apr 24 | Sky Airline
        CUZ 21:40
        14h 50m
        1 stop
        SCL 13:30
        Cusco - Santiago | Wed, Apr 29 | Sky Airline
        AU$ 300 AU$ 413
        27% off
        27% off
        AU$ 413 AU$ 300
      • SCL 04:41
        8h 29m
        1 stop
        CUZ 12:10
        Santiago - Cusco | Fri, May 8 | JetSMART Airlines
        CUZ 19:45
        7h 26m
        1 stop
        SCL 04:11
        Cusco - Santiago | Mon, May 11 | JetSMART Airlines
        AU$ 313
        24% off
        AU$ 413 AU$ 313
      • SCL 05:00
        13h 15m
        1 stop
        CUZ 17:15
        Santiago - Cusco | Thu, Jun 4 | Sky Airline
        CUZ 12:10
        7h 55m
        1 stop
        SCL 21:05
        Cusco - Santiago | Mon, Jun 8 | Sky Airline
        AU$ 318
        23% off
        AU$ 413 AU$ 318
      • SCL 19:45
        3h 30m
        Direct
        CUZ 22:15
        Santiago - Cusco | Fri, Apr 24 | LATAM Airlines
        CUZ 21:40
        14h 50m
        1 stop
        SCL 13:30
        Cusco - Santiago | Wed, Apr 29 | Sky Airline
        AU$ 320
        23% off
        AU$ 413 AU$ 320
      • SCL 20:31
        15h 44m
        1 stop
        CUZ 11:15
        Santiago - Cusco | Fri, Jun 5 | JetSMART Airlines
        CUZ 17:00
        25h 46m
        1 stop
        SCL 19:46
        Cusco - Santiago | Thu, Jun 11 | JetSMART Airlines
        AU$ 326
        21% off
        AU$ 413 AU$ 326
      • SCL 15:16
        7h 34m
        1 stop
        CUZ 21:50
        Santiago - Cusco | Sun, Apr 19 | JetSMART Airlines
        CUZ 06:50
        6h 41m
        1 stop
        SCL 14:31
        Cusco - Santiago | Sun, Apr 26 | JetSMART Airlines
        AU$ 327
        21% off
        AU$ 413 AU$ 327
      • SCL 21:25
        9h 45m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Wed, Jun 3 | LATAM Airlines
        CUZ 14:40
        3h 20m
        Direct
        SCL 19:00
        Cusco - Santiago | Sun, Jun 7 | LATAM Airlines
        AU$ 328
        21% off
        AU$ 413 AU$ 328
      • SCL 11:35
        19h 35m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Wed, Jun 3 | Sky Airline
        CUZ 21:40
        14h 50m
        1 stop
        SCL 13:30
        Cusco - Santiago | Sun, Jun 7 | Sky Airline
        AU$ 334
        19% off
        AU$ 413 AU$ 334
      • SCL 00:40
        32h 5m
        1 stop
        CUZ 07:45
        Santiago - Cusco | Wed, Apr 29 | Sky Airline
        CUZ 06:50
        13h 15m
        1 stop
        SCL 21:05
        Cusco - Santiago | Mon, May 4 | Sky Airline
        AU$ 335
        19% off
        AU$ 413 AU$ 335
      • SCL 04:41
        8h 29m
        1 stop
        CUZ 12:10
        Santiago - Cusco | Fri, Apr 24 | JetSMART Airlines
        CUZ 21:40
        14h 50m
        1 stop
        SCL 13:30
        Cusco - Santiago | Wed, Apr 29 | Sky Airline
        AU$ 336
        19% off
        AU$ 413 AU$ 336
      • SCL 13:00
        17h 25m
        1 stop
        CUZ Invalid Date
        Santiago - Cusco | Tue, Apr 14 | Normal Airline
        CUZ 15:00
        6h
        Direct
        SCL 16:00
        Cusco - Santiago | Thu, Apr 16 | Normal Airline
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      • Cheapest nonstop
        SCL 19:45
        3h 30m
        Direct
        CUZ 22:15
        Santiago - Cusco | Mon, Apr 13 | LATAM Airlines
        AU$ 162 AU$ 206
        21% off
        21% off
        AU$ 206 AU$ 162
      • SCL 11:30
        11h 19m
        1 stop
        CUZ 21:49
        Santiago - Cusco | Tue, Apr 14 | Sky Airline
        AU$ 167 AU$ 206
        19% off
        19% off
        AU$ 206 AU$ 167
      • SCL 04:56
        12h 49m
        1 stop
        CUZ 16:45
        Santiago - Cusco | Sun, May 3 | JetSMART Airlines
        AU$ 167 AU$ 206
        19% off
        19% off
        AU$ 206 AU$ 167
      • SCL 05:01
        14h 9m
        1 stop
        CUZ 18:10
        Santiago - Cusco | Fri, May 29 | JetSMART Airlines
        AU$ 168
        18% off
        AU$ 206 AU$ 168
      • SCL 04:56
        12h 4m
        1 stop
        CUZ 16:00
        Santiago - Cusco | Mon, Jun 8 | JetSMART Airlines
        AU$ 170
        17% off
        AU$ 206 AU$ 170
      • SCL 11:35
        19h 35m
        1 stop
        CUZ 06:10
        Santiago - Cusco | Mon, Apr 13 | Sky Airline
        AU$ 172
        17% off
        AU$ 206 AU$ 172
      • SCL 16:50
        16h
        1 stop
        CUZ 07:50
        Santiago - Cusco | Fri, May 29 | LATAM Airlines
        AU$ 177
        14% off
        AU$ 206 AU$ 177
      • SCL 04:55
        26h 30m
        1 stop
        CUZ 06:25
        Santiago - Cusco | Sat, Apr 25 | Sky Airline
        AU$ 180
        13% off
        AU$ 206 AU$ 180
      • SCL 05:00
        17h
        1 stop
        CUZ 21:00
        Santiago - Cusco | Wed, May 20 | Sky Airline
        AU$ 184
        11% off
        AU$ 206 AU$ 184
      • SCL 11:35
        10h 25m
        1 stop
        CUZ 21:00
        Santiago - Cusco | Sun, May 24 | Sky Airline
        AU$ 187
        9% off
        AU$ 206 AU$ 187
      • SCL 13:00
        17h 25m
        1 stop
        CUZ Invalid Date
        Santiago - Cusco | Tue, Apr 14 | Normal Airline
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Displayed flight fares from Santiago to Cusco are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Santiago to Cusco Flight Details

The distance between Santiago and Cusco is approximately 2,211.1km. It takes around 4 hours 30 minutes on average to fly from Santiago to Cusco. Based on Trip.com's data travel demand peaks in July. The off-season for travel is November.

Cheapest one-way flight priceAU$ 162
Cheapest return ticket priceAU$ 300
Off-season for travelNovember
Peak season for travelJuly
Flight distance2,211.1km
Average flight time4 hours 30 minutes
Popular airlineLATAM Airlines
Flight statistics for the Santiago–Cusco route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com Price Insights on Flights from Santiago to Cusco

What is the cheapest month for one-way flights from Santiago to Cusco?

Average price of one-way flights from Santiago to Cusco purchased by Trip.com users by month over the past 12 months.

According to Trip.com's data, the cheapest month for flights from Santiago to Cusco is November, with an average price of AU$ 260. Conversely, the most expensive month is typically January, with an average price of up to AU$ 407.

AU$ 407
AU$ 334
AU$ 260
AU$ 187
    Cheapest
  • AU$ 286
    Apr
  • AU$ 266
    May
  • AU$ 289
    Jun
  • AU$ 272
    Jul
  • AU$ 303
    Aug
  • AU$ 286
    Sep
  • AU$ 284
    Oct
  • AU$ 260
    Nov
  • AU$ 372
    Dec
  • AU$ 407
    Jan
  • AU$ 325
    Feb
  • AU$ 301
    Mar

What's the cheapest day to fly from Santiago to Cusco?

Data is based on the average flight price for each day of the week from Santiago to Cusco on Trip.com over the past 12 months.

Based on Trip.com data from the past 12 months, the cheapest day to fly from Santiago to Cusco is Sunday, with average prices lower than on other days. Avoid Thursday, as prices are usually highest then.

AU$ 354
AU$ 318
AU$ 281
AU$ 245
    Cheapest
  • AU$ 314
    Mon
  • AU$ 318
    Tue
  • AU$ 341
    Wed
  • AU$ 354
    Thu
  • AU$ 289
    Fri
  • AU$ 296
    Sat
  • AU$ 281
    Sun

When is the cheapest day to fly from Santiago to Cusco during ANZAC Day Holiday?

Data is based on the lowest one-way fares from Santiago to Cusco during ANZAC Day Holiday, sourced from the Trip.com database over the last 3 days.

ANZAC Day Holiday runs from Apr 25 to Apr 27. The cheapest flights from Santiago to Cusco are available on Apr 24, with fares starting at AU$ 169.

AU$ 236
AU$ 203
AU$ 169
AU$ 136
    Cheapest
  • AU$ 236
    22
    Apr
  • AU$ 201
    23
  • AU$ 169
    24
  • AU$ 217
    25
  • AU$ 199
    26
  • AU$ 226
    27
  • AU$ 229
    28

Flight FAQs

  • Which airlines offer the cheapest flights from Santiago (SCL) to Cusco (CUZ)?

    Based on Trip.com data, LATAM Airlines offers one-way fares as low as AU$ 162 on Cheapest nonstop routes (e.g. SCL to CUZ on Mon, Apr 13), while Sky Airline offers Cheapest nonstop round-trips from AU$ 300 departing on Fri, Apr 24 and returning on Wed, Apr 29.
  • At the moment, you can catch a direct flight from Santiago to Cusco with the following airlines, including: LATAM Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 4 hours 30 minutes to fly from Santiago (SCL) to Cusco (CUZ).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Cusco is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 9 flight per week flying from Santiago to Cusco. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: -/-/T/-/T/-/S -- LA2467 (20:02) LATAM Airlines: S/M/T/W/T/F/S -- LA2367 (15:13)
  • To find best deals on flights from Santiago to Cusco, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, Apr 13, with one-way flights priced at just AU$ 162.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Cusco travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Cusco is November, when demand for travel is lower.
  • After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Santiago to Cusco on April 15, 2026 with JetSMART, with prices starting at AU$ 138.
  • You can land at any one of the following hubs in Cusco, with Arturo Merino Benitez International Airport to Alejandro Velasco Astete International Airport (SCL-CUZ) is by far the most common option on this route: Alejandro Velasco Astete International Airport (CUZ).
  • The time difference between Cusco and Santiago is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Trip.com Airline Insights on Flights from Santiago toCusco

Which airlines offer the cheapest nonstop flights from Santiago to Cusco?

Data is based on the average price of all nonstop flights from Santiago to Cusco on Trip.com in the past 12 months.

Based on Trip.com data from the past 12 months, Sky Airline offers the cheapest nonstop flights from Santiago to Cusco, with an average price of AU$ 242.

AU$ 200
AU$ 242
AU$ 284
AU$ 326
AU$ 368
Sky Airline
AU$ 242
Sky Airline
JetSMART Airlines
AU$ 319
JetSMART Airlines
LATAM Airlines
AU$ 368
LATAM Airlines

How many flights are there each day from Santiago to Cusco?

The data is based on the flight numbers for each day of the week from Santiago to Cusco within the Trip.com database over the past month.

Based on Trip.com data from the past month, the most flights from Santiago to Cusco depart on Sunday, and the fewest flights depart on Monday/Tuesday/Thursday.

7
6
4
3
Highest
4
Mon
4
Tue
5
Wed
4
Thu
5
Fri
5
Sat
7
Sun

More Cheap Flights & Deals on Trip.com

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, regulatory fees, etc) with all fees confirmed before payment. Fees for baggage, meals, Wi-Fi, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.