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Cheap Flight Deals from Des Moines to Greenville

Discover our range of affordable one-way and round-trip flights from Des Moines to Greenville and kick-start your next adventure today!

  • One way
  • Return

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Best Time to Book Flights from Des Moines to Greenville

Explore the best time to buy affordable tickets to Greenville with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Top Airlines Flying from Des Moines to Greenville

We have a range of prices from different airlines providing flights from Des Moines to Greenville. Check below for the journey which best suits your travel needs.

Delta Air Lines
From € 159
United Airlines
From € 190
American Airlines
From € 190

Find more flights and airlines

Alternative Routes from Des Moines to Greenville

There are various non-direct routes from Des Moines to Greenville which could be cheaper and faster! Check out these alternative options to see if they could work for your trip.

  • Cheapest
    Delta Air Lines
    DSM
    07:05
    8h 39m
    1 transfer
    GSP
    16:44
    Des Moines International Airport - Greenville-Spartanburg International Airport
    Thu, Jan 16Delta Air Lines
    € 159
  • Delta Air Lines
    DSM
    07:05
    8h 39m
    1 transfer
    GSP
    16:44
    Des Moines International Airport - Greenville-Spartanburg International Airport
    Thu, Jan 16Delta Air Lines
    € 159
    Find More Flights

FAQ

  • When are flight from Des Moines (DSM) to Greenville (GSP) the cheapest?

    Airlines adjust prices for flights from Des Moines to Greenville based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much are flights from Des Moines (DSM) to Greenville (GSP) cost?

    According to Trip.com's data, the lowest price is around € 453.
  • What is the transportation method from the main airport to downtown in Greenville?

    • The distance from Greenville-Spartanburg International Airport to downtown is about 16km, by taxi about 30 minutes.
  • How many airports in Greenville (GSP)?

    There are 1 airport(s) in Greenville (GSP): Greenville-Spartanburg International Airport.

How to find a cheap flight from Des Moines to Greenville

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Des Moines to Greenville

Cheapest direct flight price€ 158
Off-season for travelNovember
Peak season for travelMarch
Flight distance1,232.43km
Popular airlineUnited Airlines