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Cheap Flight Deals from Knoxville to Columbus

For as little as US$ 193, you can take your next adventure to Columbus without breaking the bank. Choose between one-way and return tickets from Knoxville below.

  • One way
  • Return
      • TYS08:32
        4h 27m
        1 stop
        CMH12:59
        Thu, Feb 20|Knoxville - Columbus|Delta Air Lines
        US$ 193US$ 305
        37% OFF
        37% OFF
        US$ 305US$ 193

        Choose Delta Air Lines flights from Knoxville to Columbus. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Feb 20, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 193 including taxes and charges.

      • TYS12:08
        4h 44m
        1 stop
        CMH16:52
        Sat, Feb 22|Knoxville - Columbus|Delta Air Lines
        US$ 193US$ 305
        37% OFF
        37% OFF
        US$ 305US$ 193

        Choose Delta Air Lines flights from Knoxville to Columbus. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 193 including taxes and charges.

      • TYS05:45
        4h 23m
        1 stop
        CMH10:08
        Sun, Feb 23|Knoxville - Columbus|Delta Air Lines
        US$ 193US$ 305
        37% OFF
        37% OFF
        US$ 305US$ 193

        Choose Delta Air Lines flights from Knoxville to Columbus. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sun, Feb 23, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 193 including taxes and charges.

      • TYS19:23
        4h 36m
        1 stop
        CMH23:59
        Tue, Mar 11|Knoxville - Columbus|Delta Air Lines
        US$ 197
        US$ 197

        Choose Delta Air Lines flights from Knoxville to Columbus. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Mar 11, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 197 including taxes and charges.

      • TYS19:58
        3h 49m
        1 stop
        CMH23:47
        Thu, Feb 20|Knoxville - Columbus|American Airlines
        US$ 222
        US$ 222

        Choose American Airlines flights from Knoxville to Columbus. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Thu, Feb 20, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 222 including taxes and charges.

      • TYS16:16
        5h 44m
        1 stop
        CMH22:00
        Sat, Feb 22|Knoxville - Columbus|American Airlines
        US$ 222
        US$ 222

        Choose American Airlines flights from Knoxville to Columbus. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 222 including taxes and charges.

      • TYS09:55
        4h 21m
        1 stop
        CMH14:16
        Tue, Mar 11|Knoxville - Columbus|United Airlines
        US$ 222
        US$ 222

        Choose United Airlines flights from Knoxville to Columbus. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Tue, Mar 11, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 222 including taxes and charges.

      • TYS09:55
        4h 21m
        1 stop
        CMH14:16
        Thu, Feb 20|Knoxville - Columbus|United Airlines
        US$ 225
        US$ 225

        Choose United Airlines flights from Knoxville to Columbus. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Thu, Feb 20, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 225 including taxes and charges.

      • TYS09:55
        4h 23m
        1 stop
        CMH14:18
        Sat, Feb 22|Knoxville - Columbus|United Airlines
        US$ 225
        US$ 225

        Choose United Airlines flights from Knoxville to Columbus. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 225 including taxes and charges.

      • TYS05:45
        4h 7m
        1 stop
        CMH09:52
        Wed, Feb 5|Knoxville - Columbus|United Airlines
        US$ 226
        US$ 226

        Choose United Airlines flights from Knoxville to Columbus. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Wed, Feb 5, arriving at John Glenn Columbus International Airport. One-way Prices start from US$ 226 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        CMH02:00 pm
        Thu, Jan 23|Knoxville - Columbus|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Best Time to Book Flights from Knoxville to Columbus

These price trend charts carefully monitor and predict how flight prices from Knoxville to Columbus will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Alternative Routes from Knoxville to Columbus

Searching for potential routes that might be cheaper and faster? There are a few alternative ways to get to Columbus from Knoxville which could help you save money and time.

  • Cheapest
    Delta Air Lines
    TYS
    05:45
    4h 23m
    2 transfer
    CMH
    10:08
    Mcghee Tyson Airport - John Glenn Columbus International Airport
    Tue, Jan 28Delta Air Lines
    US$ 189
  • Delta Air Lines
    TYS
    05:45
    4h 23m
    2 transfer
    CMH
    10:08
    Mcghee Tyson Airport - John Glenn Columbus International Airport
    Tue, Jan 28Delta Air Lines
    US$ 189
    Find More Flights

FAQ

  • When are flight from Knoxville (TYS) to Columbus (CMH) the cheapest?

    Airlines adjust prices for flights from Knoxville to Columbus based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much are flights from Knoxville (TYS) to Columbus (CMH) cost?

    According to Trip.com's data, the lowest price is around US$ 349.

  • How many airports in Columbus (CMH)?

How to find a cheap flight from Knoxville to Columbus

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Knoxville to Columbus

Cheapest direct flight priceUS$ 178
Off-season for travelDecember
Peak season for travelOctober
Flight distance475.86km
Popular airlineUnited Airlines

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