Search Poplar Bluff Hotels

A stay at Drury Inn & Suites Poplar Bluff places you in the heart of Poplar Bluff, within a 5-minute drive of Poplar Bluff Regional Medical Center and North Main Street Historic District. This hotel is 2.6 mi (4.1 km) from Black River Coliseum and 2.7 mi (4.3 km) from Mo-Ark Regional Railroad Museum. Be sure to enjoy recreational amenities, including an outdoor pool, an indoor pool, and a hot tub. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall. Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include a business center, express check-out, and complimentary newspapers in the lobby. Free self parking is available onsite. Make yourself at home in one of the 78 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.

Welcome to the Holiday Inn Poplar Bluff, conveniently located off U.S. 60 and Business 67 on Westwood Blvd.Our hotel is the ideal choice for business near area corporations such as Briggs & Stratton, Gates Rubber, Nortek, Mid Continent Nail, Empire Comfort Systems, Poplar Bluff Regional Medical Center, and John J. Pershing VA Medical Center.Enjoy many attractions and events at Current River, Lake Wappappello, Mark Twain National Forest, Black River Coliseum, and The Historical Museum of Poplar Bluff.The Holiday Inn Poplar Bluff offers recently renovated guestrooms that feature a beautiful color scheme and comfortable design. Guest will enjoy hotel complimentary amenities, such as free Wi-Fi, Business Center, state of the art Fitness Center, and indoor pool. Hold your large or small event with us in our ballroom or boardroom.Book with us and experience hospitality at its finest!

Located in Poplar Bluff, Comfort Inn Poplar Bluff North is within a 5-minute drive of Poplar Bluff Regional Medical Center and North Main Street Historic District. This hotel is 2.8 mi (4.5 km) from Black River Coliseum and 2.9 mi (4.7 km) from Mo-Ark Regional Railroad Museum. Enjoy recreational amenities such as a 24-hour fitness center and a seasonal outdoor pool. This hotel also features complimentary wireless internet access, a television in a common area, and a banquet hall. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6 AM to 9 AM and on weekends from 7 AM to 10 AM. Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 58 air-conditioned guestrooms. Complimentary wireless internet access is available to keep you connected. Bathrooms with bathtubs or showers are provided. Conveniences include phones and desks, and housekeeping is provided daily.

Boasting a peaceful location in a quiet setting, the Hampton Inn Poplar Bluff hotel is only three miles from shops, restaurants and entertainment in the city center. Situated just off Highway 67, our welcoming Poplar Bluff hotel offers fantastic connectivity to St. Louis, Missouri and Little Rock, Arkansas. We are also within walking distance of Three Rivers College, and less than two miles from the new Poplar Bluff Regional Medical Center. Feel at home in a comfortable and modern guest room or suite, equipped with free WiFi, an ergonomic desk, a flat-screen TV, a radio alarm clock, and a bar sink. Enjoy a peaceful night’s sleep in the clean and fresh Hampton bed®, before waking up to fresh-baked waffles, fruit, yoghurt and more at Hampton’s free hot breakfast buffet. If you don’t have time to stop, just pick up a free Hampton’s On the Run Breakfast Bag™, Monday – Friday. Plunge into the inviting indoor swimming pool, or energize with the latest exercise equipment in the fitness center. With a 780 sq. ft. meeting room, and a 24-hour business center, this hotel in Poplar Bluff, MO is ideal for meetings, conferences and training sessions for up to 65 people. Our friendly staff will be on hand to make sure that your event is successful and hassle-free. Friendly service, clean rooms, comfortable surroundings, every time. If you’re not satisfied, we don’t expect you to pay. That’s our commitment and your guarantee. That's 100% Hampton®.

For easy access to Black River Coliseum stay at our Super 8 Poplar Bluff hotel. Easily accessible to Routes 60 and 67 our hotel is also nearby many outdoor recreational options including Keener Springs Recreation Area and Mark Twain National Forest making us a great choice among Poplar Bluff hotels.

Fuel up for the day and start your day right. We offer a healthy mix of delicious, fresh and free breakfast options. Choose from a wide variety of morning favorites like fresh fruit, omelets, mini waffles, sweet breads, Chobani® Greek yogurt and bacon. Then add your choice of toppings, ranging from shredded cheese and salsato sliced almonds and agave syrup. Everything you need to stay productive while on the road.

Located in Poplar Bluff, Motel 6 Poplar Bluff, MO is a 3-minute drive from Poplar Bluff Regional Medical Center and 5 minutes from Mark Twain National Forest. This motel is 4.8 mi (7.7 km) from North Main Street Historic District and 5 mi (8.1 km) from Black River Coliseum. Make use of convenient amenities such as complimentary wireless internet access, tour/ticket assistance, and a vending machine. Featured amenities include a 24-hour front desk, luggage storage, and laundry facilities. Free self parking is available onsite. Make yourself at home in one of the 73 guestrooms. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms with shower/tub combinations are provided. Conveniences include blackout drapes/curtains, as well as phones with free local calls.

Located in Williamsville, Lake Wappapello is a 1-minute drive from Mark Twain National Forest and 10 minutes from Poplar Bluff Regional Medical Center. This cabin is 8 mi (12.8 km) from North Main Street Historic District and 8.1 mi (13 km) from Margaret Harwell Art Museum. Free self parking is available onsite. Make yourself at home in one of the 13 guestrooms featuring microwaves. Conveniences include desks and separate sitting areas.