App
Customer Support
PHP
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap Flight Deals from Prague to Santiago

Whether you’re going for a one-way or round-trip to Santiago, we’ve got you covered! Check out these different flight options from Prague below.

  • One way
  • Return
      • PRG12:25
        38h 25m
        1 stop
        SCL20:50
        Wed, May 14|Prague - Santiago|Iberia
        PHP 25,225PHP 41,200
        39% OFF
        39% OFF
        PHP 41,200PHP 25,225

        Choose Iberia flights from Prague to Santiago. The one-way connecting flight with Iberia departs from Vaclav Havel Airport on Wed, May 14, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 25,225 including taxes and charges.

      • PRG19:40
        31h 10m
        1 stop
        SCL21:50
        Mon, Mar 31|Prague - Santiago|Iberia
        PHP 26,262PHP 41,200
        36% OFF
        36% OFF
        PHP 41,200PHP 26,262

        Choose Iberia flights from Prague to Santiago. The one-way connecting flight with Iberia departs from Vaclav Havel Airport on Mon, Mar 31, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 26,262 including taxes and charges.

      • PRG12:25
        38h 25m
        1 stop
        SCL21:50
        Sun, Mar 30|Prague - Santiago|Iberia
        PHP 26,901PHP 41,200
        35% OFF
        35% OFF
        PHP 41,200PHP 26,901

        Choose Iberia flights from Prague to Santiago. The one-way connecting flight with Iberia departs from Vaclav Havel Airport on Sun, Mar 30, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 26,901 including taxes and charges.

      • PRG10:30
        27h 30m
        1 stop
        SCL10:00
        Tue, Mar 18|Prague - Santiago|Vueling Airlines
        PHP 29,206
        PHP 29,206

        Choose Vueling Airlines flights from Prague to Santiago. The one-way connecting flight with Vueling Airlines departs from Vaclav Havel Airport on Tue, Mar 18, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 29,206 including taxes and charges.

      • PRG10:05
        27h 15m
        1 stop
        SCL08:20
        Tue, Apr 1|Prague - Santiago|Smartwings
        PHP 29,390
        PHP 29,390

        Choose Smartwings flights from Prague to Santiago. The one-way connecting flight with Smartwings departs from Vaclav Havel Airport on Tue, Apr 1, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 29,390 including taxes and charges.

      • PRG11:00
        27h 50m
        1 stop
        SCL09:50
        Wed, Apr 2|Prague - Santiago|Vueling Airlines
        PHP 29,398
        PHP 29,398

        Choose Vueling Airlines flights from Prague to Santiago. The one-way connecting flight with Vueling Airlines departs from Vaclav Havel Airport on Wed, Apr 2, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 29,398 including taxes and charges.

      • PRG15:35
        21h 45m
        1 stop
        SCL07:20
        Wed, Apr 9|Prague - Santiago|Iberia
        PHP 29,741
        PHP 29,741

        Choose Iberia flights from Prague to Santiago. The one-way connecting flight with Iberia departs from Vaclav Havel Airport on Wed, Apr 9, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 29,741 including taxes and charges.

      • PRG15:45
        21h 35m
        1 stop
        SCL09:20
        Wed, Mar 26|Prague - Santiago|Iberia
        PHP 30,044
        PHP 30,044

        Choose Iberia flights from Prague to Santiago. The one-way connecting flight with Iberia departs from Vaclav Havel Airport on Wed, Mar 26, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 30,044 including taxes and charges.

      • PRG10:30
        27h 30m
        1 stop
        SCL10:00
        Tue, Mar 11|Prague - Santiago|Vueling Airlines
        PHP 30,132
        PHP 30,132

        Choose Vueling Airlines flights from Prague to Santiago. The one-way connecting flight with Vueling Airlines departs from Vaclav Havel Airport on Tue, Mar 11, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 30,132 including taxes and charges.

      • PRG10:05
        38h 45m
        1 stop
        SCL20:50
        Sun, Mar 9|Prague - Santiago|Smartwings
        PHP 30,355
        PHP 30,355

        Choose Smartwings flights from Prague to Santiago. The one-way connecting flight with Smartwings departs from Vaclav Havel Airport on Sun, Mar 9, arriving at Arturo Merino Benitez Airport. One-way Prices start from PHP 30,355 including taxes and charges.

      • PRG01:00 pm
        3h 5m
        Nonstop
        SCL02:00 pm
        Wed, Feb 26|Prague - Santiago|Iberia
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Prague to Santiago Flight Time

Flight info.
Departure
Arrival
Weekly Schedule

  1. U23910

    easyJet

    09:00

    PRG

    1.5h

    10:30

    MXP

    S--W---
    Search

  2. TK1896

    Turkish Airlines

    15:10

    MXP

    3.1h

    19:15

    IST

    SMTWTFS

  3. TK215

    Turkish Airlines

    20:05

    IST

    18.7h

    07:45

    SCL

    S-TW-F-

  4. QS1056

    Smartwings

    10:05

    PRG

    3.0h

    13:05

    MAD

    S--WT-S
    Search

  5. LA705

    LATAM Airlines

    23:55

    MAD

    13.4h

    07:20

    SCL

    SMTWTFS

  6. VY8653

    Vueling Airlines

    10:50

    PRG

    2.5h

    13:20

    BCN

    SMTWTFS
    Search

  7. VY9785

    Vueling Airlines

    00:10

    BCN

    14.7h

    08:50

    SCL

    SMTWTFS

  8. QS1034

    Smartwings

    12:25

    PRG

    1.8h

    14:15

    CDG

    SMTWTFS
    Search

  9. IB582

    Iberia

    20:55

    ORY

    2.1h

    23:00

    MAD

    SMTWTF-

  10. IB117

    Iberia

    23:59

    MAD

    13.4h

    07:24

    SCL

    SMTWTFS

  11. U23904

    easyJet

    13:15

    PRG

    1.5h

    14:45

    MXP

    S--WTFS
    Search

  12. IB676

    Iberia

    19:05

    MXP

    2.4h

    21:30

    MAD

    SMTWTFS

  13. IB117

    Iberia

    23:59

    MAD

    13.4h

    07:24

    SCL

    SMTWTFS

  14. IB810

    Iberia

    15:35

    PRG

    3.2h

    18:45

    MAD

    SMTWTFS
    Search

  15. LA705

    LATAM Airlines

    23:55

    MAD

    13.4h

    07:20

    SCL

    SMTWTFS

  16. IB810

    Iberia

    15:35

    PRG

    3.2h

    18:45

    MAD

    SMTWTFS
    Search

  17. IB117

    Iberia

    23:59

    MAD

    13.4h

    07:24

    SCL

    SMTWTFS

  18. U23902

    easyJet

    21:35

    PRG

    1.5h

    23:05

    MXP

    SMTWT-S
    Search

  19. TK1896

    Turkish Airlines

    15:10

    MXP

    3.1h

    19:15

    IST

    SMTWTFS

  20. TK215

    Turkish Airlines

    20:05

    IST

    18.7h

    07:45

    SCL

    S-TW-F-

  21. DY1505

    Norwegian Air Shuttle ASA

    21:55

    PRG

    1.9h

    23:50

    OSL

    ---W---
    Search

  22. DY1718

    Norwegian Air Shuttle ASA

    07:45

    OSL

    3.8h

    11:30

    MAD

    -M-W-FS

  23. LA707

    LATAM Airlines

    13:25

    MAD

    13.4h

    20:50

    SCL

    S----F-

  24. U28784

    easyJet

    21:55

    PRG

    2.1h

    23:00

    LGW

    SM-WT-S
    Search

  25. VY7827

    Vueling Airlines

    14:30

    LGW

    2.3h

    17:45

    BCN

    SMTWTFS

  26. VY9785

    Vueling Airlines

    00:10

    BCN

    14.7h

    08:50

    SCL

    SMTWTFS
Find more flights and airlines

Best Time to Book Flights from Prague to Santiago

Explore the best time to buy affordable tickets to Santiago with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When are flight from Prague (PRG) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Prague to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much are flights from Prague (PRG) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around PHP 79,720.

  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12km, by taxi about 30 minutes.

  • How many airports in Santiago (SCL)?

    There are 1 airport(s) in Santiago (SCL): Arturo Merino Benitez Airport.

How to find a cheap flight from Prague to Santiago

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Prague to Santiago

Cheapest direct flight pricePHP 25,225
Off-season for travelMarch
Peak season for travelNovember
Flight distance12,463.36km
Popular airlineAir France

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.