5-Star Hotels in Mississippi, United States

5-Star Hotels in Mississippi, United States

Enter your dates for the latest hotel rates and availability.

Scroll down to see hotels
Filter by:
Hotel Star Rating
≤2345
Guest Rating
Amazing 9+Great 8+Good 7+Pleasant 6+

Top 5-Star Hotels - Mississippi

Choose your travel dates to see the latest prices
Most Booked
Lowest price
Closest to downtown
Highest Rated
Hard Rock Hotel & Casino Biloxi Hotels in
Hard Rock Hotel & Casino Biloxi Hotels in Hard Rock Hotel & Casino Biloxi Hotels in
Hotels in Mississippi
AAngela Flora 2025.06.02
If you're seeing a show, this is the best choice for an overnight or weekend stay! There's so many food choices. The pool area is so nice. Really enjoyed my stay and the concert!!
Very Good
106 reviews
8.3/10
Price from
VND 2,524,259
per night
Check Availability
Luxury Home with Beach Views with Pool/Spa Hotels in
Luxury Home with Beach Views with Pool/Spa Hotels in Luxury Home with Beach Views with Pool/Spa Hotels in
Hotels in Mississippi
Relax with the family at this peaceful home with porches upstairs and down, you can enjoy coastal breezes overlooking the ocean and gorgeous oaks in a beautiful new construction area only a 1-2 min drive from downtown restaurants, shopping, and attractions! This 3 bedroom home has spacious bedrooms, with televisions, ceiling fans, comfortable beds, and lovely decor! 2 car garage with parking for 4 and extra street parking. Walkable to the beach with beautiful finishes and easy access to downtown. Absolutely gorgeous heated pool and spa with a covered area and television outside.About pets:No pets allowed.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Outstanding
10.0/10
Check Availability
The Luxe on Main is an Ultra-Modern, Trendy New Construction in Downtown BSL. Hotels in
The Luxe on Main is an Ultra-Modern, Trendy New Construction in Downtown BSL. Hotels in The Luxe on Main is an Ultra-Modern, Trendy New Construction in Downtown BSL. Hotels in
Hotels in Mississippi
Property DescriptionThe Luxe on Main is an ultra-modern, trendy new construction nestled in the heart of downtown Bay St. Louis on historic Main Street. It was designed with luxury and comfort as top priorities by John and Allison Anderson of Unabridged Architecture with the construction overseen by Ronnie Cuevas. The home's exquisite architecture includes an abundance of large windows and glass doors, vaulted wood ceilings, iron turnbuckle supports, and an open floor plan. It also features beautiful mural art throughout by local artist, Nikki Main, and is filled with handcrafted oak furniture by Blalock Furniture and Design. The exquisite kitchen has floor to ceiling custom cabinets and an oversized island that is perfect for entertaining. You will not find another property like The Luxe on Main anywhere else along the Mississippi Gulf Coast. This Boujee property truly is one-of-a-kind. Location DetailsLocated about 50 miles from the City of New Orleans and about 16 miles from Gulfport, it is bordered by the Gulf of Mexico and the Bay of St. Louis. Surrounded by white sand beaches, Bay St. Louis is known for its beautiful natural setting. Just a few blocks away you'll find Old Town Bay St. Louis, a walkable downtown area lined with restaurants, bars, live music, art galleries, and local shops. This area is a Leisure and Recreation District and a golf cart approved community. In 2022, Bay St. Louis took second place in USA Today’s 10 Best Coastal Small Towns, stating, “The quaint seaside town of Bay St. Louis calls itself ‘a place apart,’ and it’s easy to see why. The friendly community has everything you’d want from a small-town seaside escape – a store-lined Main Street, restaurants serving fresh Gulf seafood, museums and an 8.5-mile canoe and kayak trail.”Bay St. Louis was also ranked by Southern Living Magazine as one of the Best Small Towns in the South 2023, which stated, “Just over 50 miles from New Orleans, Bay St. Louis blends the Big Easy’s funky, artsy feel with the mellow, barefoot vibe you can find only in a tried-and-true coastal town. The beaches are dog-friendly, the blueways (water trails) are ready for exploring, and Old Town’s French Quarter appeal can’t be beat.”Whether you are seeking romance, fun in the sun, partying or tranquility, Bay St. Louis delivers and will not disappoint.About The SpaceWelcome to The Luxe on Main, a Luxury Property and the Perfect Vacation Rental.Suite a accommodates up to 8 Guests very comfortably with 2 King Bedrooms | 1 Bunkroom with 2 Full Beds and 2 Twin Beds | 3 Full Bathrooms | Gourmet Kitchen | Living Room | Front Porch | Outdoor Patio | YardSuite b accommodates up to 4 Guests very comfortably with 2 King Bedrooms | 2 Full Bathrooms | Gourmet Kitchen | Living Room | Outdoor Patio | YardFor large groups or families, Suites a and b have a common door that allow for the property to accommodate up to 12 Guests in comfort. Go to VRBO Property ID 3960414 to book Suite a and b together. Inside this first-class home is pure elegance with vaulted ceilings and chic décor. Expansive windows and glass doors flood the home with golden sunlight, providing an inviting atmosphere. Each suite boasts its own private outdoor area complete with Adirondack lounge chairs and table by Loll Designs and a Weber Grill. Staying committed to a 5-star standard, we supply the following for your stay: Yeti drinkware, Cozy Earth waffle towels, Cozy Earth robes, high quality bamboo sheets, iron with ironing board, complimentary shampoo, conditioner and body wash, toilet paper, paper towels, trash bags, dishwasher and laundry pods, dish soap, and plastic trash bags. In the middle of everything that makes up Bay St. Louis, this one is a must stay! Savor the Gulf South Lifestyle with True Luxury!Suite bOpen concept living with large windows and glass doors. High vaulted ceilings! Equipped with 2 king bed bedrooms and 2 full bathrooms, living room, well-appointed gourmet kitchen with an extra-large quartz island. This newly built home provides all BRAND-NEW luxury furnishings.Living Room• Soaring Floor to Ceiling Windows and Doors• Cozy-Warm Atmosphere with Brand New Modern-Chic Furnishings• Floating Media Center• Large Overstuffed Pillow Sofa• (2) Leather Tufted Accent Chairs• Counter Height Table with 6 Chairs (Chairs are interchangeable with Kitchen Island Chairs)• Table accented with a Succulent Garden• 86″ Smart TV • Sonos In Wall Architectural Speakers with Blue Tooth Connectivity• Access to Outdoor PatioKitchen• Extra Large Quartz Dine-In Island with 4 Chairs (Chairs are interchangeable with Living Room Table)• Floor to Ceiling Custom Kitchen Cabinets• Fully Appointed Gourmet Kitchen with Stainless Steel Appliances• Whirlpool Dishwasher• Whirlpool Gas Stove + Air Fry Oven• Whirlpool Microwave• Whirlpool French Door Refrigerator + Freezer + Ice Maker • Garbage Disposal with Push Button Switch on Island • Toaster Oven• Dinnerware, Glassware, Flatware• 11.5” Serving Platters – Set of Two• Porcelain Baking Dishes – Set of Four (9”, 11” 12” and 15”)• Cuisinart Knife Block Set• Cuisinart Chef’s Classic Pro NonStick 11- Piece Cookware Set:• 8-inch Skillet, • 10-inch Skillet• 1.5 qt Covered Saucepan• 2.5 qt Covered Saucepan• 3 qt Covered Sauté Pan• 8 qt Covered Stockpot• Steamer Insert• Cuisinart 6-piece bakeware Pan Set:• 9" Loaf Pan• 9" Square Cake Pan• 9" Round Cake Pan Set of 2• 6 Cup Muffin Pan• 17" Baking Sheet• Cutting Boards• Large Measuring Cup• Cuisinart 5 qt Hard Mesh Colander• Stainless Steel Box Grater• KitchenAid Pizza Wheel• KitchenAid Tool Set: • Slotted Turner• Basting Spoon• Scraper Spatula• Euro Peeler• Can Opener• Utility Whisk• 4 Measuring Cups• 5 Measuring Spoons• Oster Blender (48 Ounce Capacity)• Cuisinart Coffee Center 12 cup coffeemaker and single -serve brewer (K-Cups compatible)• (4) Custom Yeti Rambler 30 oz Tumblers with Magslide Lids • (4) Custom Yeti Rambler 10 oz Wine Tumblers with Magslide Lids• Stemmed Wine Glassware• BBQ UtensilsMaster Bedroom/Bath• King Size Bed• Floating Night Stands on Each Side of the Bed• Sconce Lighting & Control Switch on Each Side of the Bed• Storage Drawers under Bed• Floor to Ceiling Sliding Door• Door Access to Yard• Closet + Luggage Rack• 50″ Smart TV • USB Outlets on Each Side of the Bed (Type A and Type C)• Ceiling Fan with Light • Room Black Out Blinds• Private En-Suite Bathroom with Large Mirror • Kohler Fixtures• Panasonic Whisper Warm in Ceiling Heater and Fan • Large Walk-In Shower with Glass Surround• Two Cozy Earth Waffle Bath RobesGuest Bedroom/Bath• King Size Bed• Floating Night Stands on Each Side of the Bed• Sconce Lighting & Control Switch on Each Side of the Bed• Storage Drawers under Bed• Window with View of Yard • Closet + Luggage Rack• 50″ Smart TV • USB Outlets on Each Side of the Bed (Type A and Type C)• Ceiling Fan with Light• Room Black Out Blinds • Bathroom with Single Sink and Glass Surround Tub/Shower• Kohler Fixtures• Panasonic Whisper Warm in Ceiling Heater and Fan Patio• (4) Loll Designs Adirondack Lounge Chairs and Table• (2) Outdoor Ceiling Fans with Lights • Outdoor Sonos Outdoor Speakers with Blue Tooth Connectivity• Weber Grill (Propane and BBQ Utensils Provided)• Rear Yard Illuminated by Hanging Lights• Privacy Fence with Mural Art by Local Artist Nikki MainLaundry• Full size GE High Efficiency Washer & Dryer • Iron / Ironing Board• Laundry Detergent & Pods ProvidedEntertainment• Smart TVs Throughout• Sonos In Wall Architectural Speakers with Blue Tooth Connectivity• YouTube TV Provided by Owner (Netflix, Hulu, Max, Prime Apps guests use their login)• BooksHeating & Cooling• Rheem Central Air Conditioning / Heating• Ceiling Fans in Each Bedroom• Rinnai Tankless Water HeaterHome Safety• Security cameras covering exterior of property. Cameras are on 24/7• Smoke alarm• Carbon Monoxide Detector• Fire extinguisher • Security Alarm• Exterior Lights with Motion SensorsInternet• High Speed Wi-Fi Throughout + Wired Wifi ExtendersOff Street Parking• Large Driveway Providing Ample Off-Street Parking (See Parking Diagram)• Covered Carport for Unit b Self Check-In• Smart Lock Keyless Entry Box (Code Provided)About pets:Pets allowed: dogs less than 20 lbs per pet (limit one pet total).Please no pets on the furniture..About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.Please be mindful this home is NOT childproof..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:Events allowed: family gatherings, birthday parties, weddings.Maximum event attendees: 15.
Outstanding
5 reviews
10.0/10
Check Availability
One block from Main Street, short ride to Oxford, Enid, Sardis and Grenada Lakes Hotels in
One block from Main Street, short ride to Oxford, Enid, Sardis and Grenada Lakes Hotels in One block from Main Street, short ride to Oxford, Enid, Sardis and Grenada Lakes Hotels in
Hotels in Mississippi
The whole group will enjoy access to everything from this centrally located place. One block from Water Valleys picturesque Main Street and a short drive to Oxford. If on a fishing trip it’s a quick drive to Enid, Sardis and Grenada Lakes.About pets:Pets allowed: dogs (limit 2 total).About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About customRules:please pick up after your pet.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About events:No events allowed.
Outstanding
19 reviews
10.0/10
Check Availability
“THE BAY STAY”  3BR - 2BA Canal Home with Boat Pier, Fish Off Dock, Cart to Town Hotels in
“THE BAY STAY”  3BR - 2BA Canal Home with Boat Pier, Fish Off Dock, Cart to Town Hotels in “THE BAY STAY”  3BR - 2BA Canal Home with Boat Pier, Fish Off Dock, Cart to Town Hotels in
Hotels in Mississippi
Welcome to “THE BAY STAY” Waterfront 3BR/2BA Home on Canal with Private Boat Pier. Enjoy laid-back comfort at The Bay Stay, a newly built and beautifully furnished 3-bedroom, 2-bath home in Bay St. Louis. Nestled on a quiet canal, this property features a private boat pier where you can fish or tie up your boat after a day on the water.The interior offers modern finishes, open living spaces, and a fully equipped kitchen with everything you need to prepare meals. Bedrooms are spacious and thoughtfully decorated, with clean, comfortable linens. Located in a golf cart-friendly area, you’re just a short cart ride to Old Town’s shops, restaurants, beach, and marina. Golf cart rental options are nearby. Whether you're coming to explore the coast, relax, or fish off the dock, this home is the perfect base for your Bay St. Louis getaway.Highlights:3 bedrooms / 2 bathroomsSleeps 6–8Private boat pier Fully equipped kitchen (no food included)Washer/dryer, Wi-Fi, smart TVAmple parking, including boat trailer space10-minute golf cart ride to Old TownEnjoy a peaceful retreat with the charm, access, and comfort of the Mississippi Gulf Coast.About pets:No pets allowed, service animals permitted.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.Supervise at all times. risk canal elevated space.About customRules:No parking on the street..Children must be supervised at all times.,Guests assume all risks related to the use of the property, including not limited to the stairs, balcony, dock, and BBQ..About checkIn:Check in after 3:00 PM.About smoking:Smoking allowed: in designated areas.Outdoor smoking only on the porch, under-house.About minBookingAge:Minimum age to rent: 24.About events:No events allowed.
Outstanding
5 reviews
10.0/10
Check Availability
3Br/2BA Bottlebrush on Bowen - Perfect Location Ocean Springs. Walk to Downtown! Hotels in
3Br/2BA Bottlebrush on Bowen - Perfect Location Ocean Springs. Walk to Downtown! Hotels in 3Br/2BA Bottlebrush on Bowen - Perfect Location Ocean Springs. Walk to Downtown! Hotels in
Hotels in Mississippi
Only one block to the heart of the downtown shopping/restaurant district, Bottlebrush on Bowen is a beautiful, meticulously maintained three-bedroom property within easy walking distance to historic downtown Ocean Springs, and less than a mile to beautiful Front Beach.Newly remodeled with all the amenities you need, Bottlebrush on Bowen is the perfect place for a romantic weekend getaway, as well as week-long vacations with the family. Loaded with amenities, you will find a clean, impeccably decorated space with hardwood floors throughout and all the conveniences of home. Bottlebrush on Bowen features a large open kitchen with stainless steel appliances and marble counters. The custom cabinets are filled with virtually everything you will need to prepare your meals.In the large dining area accented by chandelier lighting and decorated with elegant works of art by New Orleans artist Billy Solitario, the marble table is perfect for romantic dinners, and the large marble floating kitchen island offers additional dining space that kids love.The kitchen features stainless steel appliances and offers plenty of space for preparing meals on days you rather stay in the comforts of home, rather than eating out at the numerous Ocean Springs hot spots.The living room provides a comfortable place to lounge in front of the large flat-screen TV with Cable and provides an extra place to sleep if needed. In the Master Bedroom you will find a luxurious, memory foam King bed, a huge walk-in closet, and the private bathroom features his and her vanities, an elegant walk-in shower, as well as a large tub (we are waiting on a part to fix the jets, so it is only a standard bathtub, not jacuzzi). Bottlebrush on Bowen has an on-demand tankless hot water heater, so no worries about having to wait for hot water if you have larger groups or like to take long hot showers.The two guest bedrooms have a queen-size bed and a double. All have flat-screen TVs with cable. A covered porch in the back of the home is surrounded by nature, perfect for relaxing or entertaining. A grill is available for cooking out, and there are bikes available for guest use to explore the area. ***Pets are allowed for a $150 non-refundable pet fee. Please select that you will be bringing a pet when making the reservation or we will need to send an additional payment request after booking******There should be no more than six people on the property unless prior permission is given. No events or parties of any kind. We have installed exterior security cameras for the safety of both guests and property outside of the home. There are no inside cameras.***Ocean Springs is a golf cart-friendly town, and we rent a golf cart for guest use. Please inquire on the price before or during your stay.The property is equipped with high-speed wireless Internet, 4 flat-screen TVs, and much more. While at Bottlebrush on Bowen, you’ll feel completely at home and never need to leave the property to have a fantastic stay. But if you can tear yourself away, you ll find yourself in the heart of the quaint historic town of Ocean Springs. It has many great restaurants, museums, art galleries, sidewalk cafes, antique stores, and unique gift shops for you to enjoy.Bottlebrush on Bowen is the perfect place for your vacation. Book your stay today!About pets:Pets allowed: dogs less than 50 lbs per pet (limit 2 pets total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About customRules:Quiet ours are 9pm-9am.No RVs,$150 non-refundable pet fee for those bringing dogs.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.Smoking is allowed in outdoor areas only.About minBookingAge:Minimum age to rent: 24.About events:No events allowed.
Outstanding
60 reviews
9.8/10
Check Availability
See All 5-Star Hotels in Mississippi

FAQ

How do I book a hotel on Trip.com?

To book a hotel on Trip.com, simply enter your destination, travel dates, and the number of guests on the page. Then, browse through the available hotels and select the one you want to book. Follow the prompts to enter your payment information and complete the booking.

How do I get hotel deals on Trip.com?

There are several ways to find affordable hotels on Trip.com. You can narrow down your search results by filtering hotels according to your preferred price range, or you can sort the results by price to view the cheapest options first.

Where can I find hotel deals on Trip.com?

Trip.com offers a wide variety of hotel deals and promotions that are available throughout the year. You can easily find these special offers on our deals page. What's more, if you are a member of our loyalty program, you can sign in to your account and discover exclusive discounted rates at hotel list pages.

How can I get lower prices for hotels?

Sometimes booking hotels midweek is cheaper, but it also depends on the season.

How many hotels are listed on Trip.com?

You’ll find over 1,500,000 hotels in 230+ countries and regions on Trip.com. Can’t decide which hotel to book? Browse the site for inspiration!

Can I cancel or change my hotel bookings on Trip.com?

It depends on the hotel policy and date of cancellation. Please check the policy section of the related hotel pages. To cancel or change your bookings, sign in to your Trip.com account, go to "My Bookings", and follow the instructions.

How do I contact Trip.com customer support?

You can contact Trip.com's 24/7 customer support by visiting the Help Center on Trip.com and submitting a request. You can also contact us by phone or service chat, depending on your location.

Property Information for Tourists

Total Properties6
Number of Reviews170
Highest PriceVND 26,504,725
Lowest PriceVND 1,692,827
Weekend Avg. PriceVND 8,426,682
Weekday Avg. PriceVND 4,130,947